HEMATOLOGICAL PROFILE OF DENGUE PATIENTS: INSIGHTS FROM A TERTIARY CARE CENTRE STUDY

Samenvatting

Introduction: Dengue fever is a viral infection that is transmitted primarily by Aedes mosquitoes. Hematological characteristics encompass alterations or irregularities detected in the bloodstream of individuals affected with dengue fever. It is imperative to acknowledge that the course and intensity of dengue can differ, and patients may not manifest identical hematological characteristics.
Aims and Objectives: To study hematological characteristics of dengue disease patients.
Material and Method: A total 200, IgM positive patients, the study's rigorous research methodology is applied to investigate the characteristics and prevalence of dengue fever. The study takes place in a tertiary care center. The study involves careful data collection, SPSS statistical analysis, and ethical considerations.
Result: The Study’s result presents a demographic and hematological profile of 200 respondents with dengue fever. The majority of respondents are in the age range of 21-30 (29%) and 15-20 (27%), with 63.5% being male. Leukocyte count reveals 51.5% with counts <4000, while hematocrit levels show 54.5% with levels <40%. Thrombocytopenia grades indicate 60.5% with moderate thrombocytopenia. Hemoglobin levels range predominantly from 12-15 (57%). Bleeding manifestations are present in 14%, with a correlation between thrombocytopenia and bleeding. The clinical spectrum includes 84% with dengue fever (DF), 14% with dengue hemorrhagic fever (DHF), and 2% with dengue shock syndrome (DSS).
Conclusion: A definitive evident found that hematological profile affects significantly in dengue patients. As the severity of thrombocytopenia rises, the likelihood of experiencing bleeding manifestations also increases.