Comparative Analysis of Analgesic Efficacy: Continuous Femoral Nerve Block vs. Intravenous Morphine

Abstract

Background: Total knee arthroplasty (TKA) is associated with significant postoperative pain, necessitating effective analgesia for optimal recovery. This study aimed to compare the analgesic efficacy of continuous femoral nerve block (CFNB) and patient-controlled analgesia (PCA) using intravenous morphine post-TKA.
Methods: A randomized controlled trial enrolled [number] patients undergoing TKA, randomly allocating them to CFNB with a local anesthetic catheter or PCA with intravenous morphine. Pain scores, opioid consumption, adverse effects, and patient satisfaction were assessed.
Results: The CFNB group demonstrated consistently lower pain scores across various time points post-TKA compared to the PCA group ([mean difference] at 48 hours [value], p < 0.05). Opioid consumption within 48 hours was significantly lower in the CFNB group ([mean difference], p < 0.05). Adverse effects, including nausea, vomiting, and sedation, were reduced in the CFNB cohort.
Conclusion: Continuous femoral nerve block (CFNB) exhibited superior analgesic efficacy compared to patient-controlled analgesia (PCA) with intravenous morphine post-total knee arthroplasty (TKA). CFNB resulted in lower pain scores, reduced opioid consumption, and fewer adverse effects, highlighting its potential as a preferred analgesic modality in TKA patients.
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