Evaluation of serum mineral micronutrients (Zn, Cu, Fe, Mg) and their correlation with clinical parameters (gingival index, probing pocket depth, clinical attachment loss) in chronic periodontitis patients

Abstract

Background: Periodontitis, as a common chronic infectious disease in dentistry, is mediated by the immune-inflammatory response to the accumulated periodontal pathogens in the periodontal tissues, which involves both innate and acquired immunity. Aims and objectives: To evaluate serum mineral micronutrients (Zn, Cu, Fe, and Mg) and their correlation with clinical parameters (gingival index, probing pocket depth, clinical attachment loss) in chronic periodontitis subjects.
Materials and methods: A total of 100 subjects were enrolled. 50 were in the case group and 50 in the control group. The age of the subjects was between 30 and 60 years. The data was collected and analysed using SPSS software. An independent t-test was done. The chi-square test was done. P <0.05 was considered significant.
Results: Mean Cu and Fe levels were significantly higher in the chronic periodontitis group in comparison to the control group, while mean Zn and Mg levels were significantly lower in the chronic periodontitis group in comparison to the control group. Conclusion: Serum zinc and magnesium levels showed a negative correlation with periodontal clinical parameters (gingival index, PPD, and clinical attachment loss)..